Similarity of
2lc8-m10_A_G_4_G_5 2lc8-m1_A_G_4_G_5 2lc8-m2_A_G_4_G_5 2lc8-m3_A_G_4_G_5 2lc8-m4_A_G_4_G_5 2lc8-m5_A_G_4_G_5 2lc8-m6_A_G_4_G_5 2lc8-m7_A_G_4_G_5 2lc8-m8_A_G_4_G_5 2lc8-m9_A_G_4_G_5 2lc8-m10_A_G_5_U_6 2lc8-m1_A_G_5_U_6 2lc8-m2_A_G_5_U_6 2lc8-m3_A_G_5_U_6 2lc8-m4_A_G_5_U_6 2lc8-m5_A_G_5_U_6 2lc8-m6_A_G_5_U_6 2lc8-m7_A_G_5_U_6 2lc8-m8_A_G_5_U_6 2lc8-m9_A_G_5_U_6 2lc8-m10_A_U_6_C_7 2lc8-m1_A_U_6_C_7 2lc8-m2_A_U_6_C_7 2lc8-m3_A_U_6_C_7 2lc8-m4_A_U_6_C_7 2lc8-m5_A_U_6_C_7 2lc8-m6_A_U_6_C_7 2lc8-m7_A_U_6_C_7 2lc8-m8_A_U_6_C_7 2lc8-m9_A_U_6_C_7 2lc8-m10_A_C_7_A_8 2lc8-m1_A_C_7_A_8 2lc8-m2_A_C_7_A_8 2lc8-m3_A_C_7_A_8 2lc8-m4_A_C_7_A_8 2lc8-m5_A_C_7_A_8 2lc8-m6_A_C_7_A_8 2lc8-m7_A_C_7_A_8 2lc8-m8_A_C_7_A_8 2lc8-m9_A_C_7_A_8 2lc8-m10_A_A_8_G_9 2lc8-m1_A_A_8_G_9 2lc8-m2_A_A_8_G_9 2lc8-m3_A_A_8_G_9 2lc8-m4_A_A_8_G_9 2lc8-m5_A_A_8_G_9 2lc8-m6_A_A_8_G_9 2lc8-m7_A_A_8_G_9 2lc8-m8_A_A_8_G_9 2lc8-m9_A_A_8_G_9 2lc8-m10_A_G_9_G_10 2lc8-m1_A_G_9_G_10 2lc8-m2_A_G_9_G_10 2lc8-m3_A_G_9_G_10 2lc8-m4_A_G_9_G_10 2lc8-m5_A_G_9_G_10 2lc8-m6_A_G_9_G_10 2lc8-m7_A_G_9_G_10 2lc8-m8_A_G_9_G_10 2lc8-m9_A_G_9_G_10 2lc8-m10_A_G_10_G_11 2lc8-m1_A_G_10_G_11 2lc8-m2_A_G_10_G_11 2lc8-m3_A_G_10_G_11 2lc8-m4_A_G_10_G_11 2lc8-m5_A_G_10_G_11 2lc8-m6_A_G_10_G_11 2lc8-m7_A_G_10_G_11 2lc8-m8_A_G_10_G_11 2lc8-m9_A_G_10_G_11 2lc8-m10_A_G_11_U_12 2lc8-m1_A_G_11_U_12 2lc8-m2_A_G_11_U_12 2lc8-m3_A_G_11_U_12 2lc8-m4_A_G_11_U_12 2lc8-m5_A_G_11_U_12 2lc8-m6_A_G_11_U_12 2lc8-m7_A_G_11_U_12 2lc8-m8_A_G_11_U_12 2lc8-m9_A_G_11_U_12 2lc8-m10_A_U_12_C_13 2lc8-m1_A_U_12_C_13 2lc8-m2_A_U_12_C_13 2lc8-m3_A_U_12_C_13 2lc8-m4_A_U_12_C_13 2lc8-m5_A_U_12_C_13 2lc8-m6_A_U_12_C_13 2lc8-m7_A_U_12_C_13 2lc8-m8_A_U_12_C_13 2lc8-m9_A_U_12_C_13 2lc8-m10_A_C_13_A_14 2lc8-m1_A_C_13_A_14 2lc8-m2_A_C_13_A_14 2lc8-m3_A_C_13_A_14 2lc8-m4_A_C_13_A_14 2lc8-m5_A_C_13_A_14 2lc8-m6_A_C_13_A_14 2lc8-m7_A_C_13_A_14 2lc8-m8_A_C_13_A_14 2lc8-m9_A_C_13_A_14 2lc8-m10_A_A_14_G_15 2lc8-m1_A_A_14_G_15 2lc8-m2_A_A_14_G_15 2lc8-m3_A_A_14_G_15 2lc8-m4_A_A_14_G_15 2lc8-m5_A_A_14_G_15 2lc8-m6_A_A_14_G_15 2lc8-m7_A_A_14_G_15 2lc8-m8_A_A_14_G_15 2lc8-m9_A_A_14_G_15 2lc8-m10_A_G_15_G_16 2lc8-m1_A_G_15_G_16 2lc8-m2_A_G_15_G_16 2lc8-m3_A_G_15_G_16 2lc8-m4_A_G_15_G_16 2lc8-m5_A_G_15_G_16 2lc8-m6_A_G_15_G_16 2lc8-m7_A_G_15_G_16 2lc8-m8_A_G_15_G_16 2lc8-m9_A_G_15_G_16 2lc8-m10_A_G_16_A_17 2lc8-m1_A_G_16_A_17 2lc8-m2_A_G_16_A_17 2lc8-m3_A_G_16_A_17 2lc8-m4_A_G_16_A_17 2lc8-m5_A_G_16_A_17 2lc8-m6_A_G_16_A_17 2lc8-m7_A_G_16_A_17 2lc8-m8_A_G_16_A_17 2lc8-m9_A_G_16_A_17 2lc8-m10_A_A_17_G_18 2lc8-m1_A_A_17_G_18 2lc8-m2_A_A_17_G_18 2lc8-m3_A_A_17_G_18 2lc8-m4_A_A_17_G_18 2lc8-m5_A_A_17_G_18 2lc8-m6_A_A_17_G_18 2lc8-m7_A_A_17_G_18 2lc8-m8_A_A_17_G_18 2lc8-m9_A_A_17_G_18 2lc8-m10_A_G_18_C_19 2lc8-m1_A_G_18_C_19 2lc8-m2_A_G_18_C_19 2lc8-m3_A_G_18_C_19 2lc8-m4_A_G_18_C_19 2lc8-m5_A_G_18_C_19 2lc8-m6_A_G_18_C_19 2lc8-m7_A_G_18_C_19 2lc8-m8_A_G_18_C_19 2lc8-m9_A_G_18_C_19 2lc8-m10_A_C_19_C_20 2lc8-m1_A_C_19_C_20 2lc8-m2_A_C_19_C_20 2lc8-m3_A_C_19_C_20 2lc8-m4_A_C_19_C_20 2lc8-m5_A_C_19_C_20 2lc8-m6_A_C_19_C_20 2lc8-m7_A_C_19_C_20 2lc8-m8_A_C_19_C_20 2lc8-m9_A_C_19_C_20 2lc8-m10_A_C_20_C_21 2lc8-m1_A_C_20_C_21 2lc8-m2_A_C_20_C_21 2lc8-m3_A_C_20_C_21 2lc8-m4_A_C_20_C_21 2lc8-m5_A_C_20_C_21 2lc8-m6_A_C_20_C_21 2lc8-m7_A_C_20_C_21 2lc8-m8_A_C_20_C_21 2lc8-m9_A_C_20_C_21 2lc8-m10_A_C_21_C_22 2lc8-m1_A_C_21_C_22 2lc8-m2_A_C_21_C_22 2lc8-m3_A_C_21_C_22 2lc8-m4_A_C_21_C_22 2lc8-m5_A_C_21_C_22 2lc8-m6_A_C_21_C_22 2lc8-m7_A_C_21_C_22 2lc8-m8_A_C_21_C_22 2lc8-m9_A_C_21_C_22 2lc8-m10_A_C_22_C_23 2lc8-m1_A_C_22_C_23 2lc8-m2_A_C_22_C_23 2lc8-m3_A_C_22_C_23 2lc8-m4_A_C_22_C_23 2lc8-m5_A_C_22_C_23 2lc8-m6_A_C_22_C_23 2lc8-m7_A_C_22_C_23 2lc8-m8_A_C_22_C_23 2lc8-m9_A_C_22_C_23 2lc8-m10_A_C_23_C_24 2lc8-m1_A_C_23_C_24 2lc8-m2_A_C_23_C_24 2lc8-m3_A_C_23_C_24 2lc8-m4_A_C_23_C_24 2lc8-m5_A_C_23_C_24 2lc8-m6_A_C_23_C_24 2lc8-m7_A_C_23_C_24 2lc8-m8_A_C_23_C_24 2lc8-m9_A_C_23_C_24 2lc8-m10_A_C_24_C_25 2lc8-m1_A_C_24_C_25 2lc8-m2_A_C_24_C_25 2lc8-m3_A_C_24_C_25 2lc8-m4_A_C_24_C_25 2lc8-m5_A_C_24_C_25 2lc8-m6_A_C_24_C_25 2lc8-m7_A_C_24_C_25 2lc8-m8_A_C_24_C_25 2lc8-m9_A_C_24_C_25 2lc8-m10_A_C_25_C_26 2lc8-m1_A_C_25_C_26 2lc8-m2_A_C_25_C_26 2lc8-m3_A_C_25_C_26 2lc8-m4_A_C_25_C_26 2lc8-m5_A_C_25_C_26 2lc8-m6_A_C_25_C_26 2lc8-m7_A_C_25_C_26 2lc8-m8_A_C_25_C_26 2lc8-m9_A_C_25_C_26 2lc8-m10_A_C_26_U_27 2lc8-m1_A_C_26_U_27 2lc8-m2_A_C_26_U_27 2lc8-m3_A_C_26_U_27 2lc8-m4_A_C_26_U_27 2lc8-m5_A_C_26_U_27 2lc8-m6_A_C_26_U_27 2lc8-m7_A_C_26_U_27 2lc8-m8_A_C_26_U_27 2lc8-m9_A_C_26_U_27 2lc8-m10_A_U_27_G_28 2lc8-m1_A_U_27_G_28 2lc8-m2_A_U_27_G_28 2lc8-m3_A_U_27_G_28 2lc8-m4_A_U_27_G_28 2lc8-m5_A_U_27_G_28 2lc8-m6_A_U_27_G_28 2lc8-m7_A_U_27_G_28 2lc8-m8_A_U_27_G_28 2lc8-m9_A_U_27_G_28 2lc8-m10_A_G_28_A_29 2lc8-m1_A_G_28_A_29 2lc8-m2_A_G_28_A_29 2lc8-m3_A_G_28_A_29 2lc8-m4_A_G_28_A_29 2lc8-m5_A_G_28_A_29 2lc8-m6_A_G_28_A_29 2lc8-m7_A_G_28_A_29 2lc8-m8_A_G_28_A_29 2lc8-m9_A_G_28_A_29 2lc8-m10_A_A_29_A_30 2lc8-m1_A_A_29_A_30 2lc8-m2_A_A_29_A_30 2lc8-m3_A_A_29_A_30 2lc8-m4_A_A_29_A_30 2lc8-m5_A_A_29_A_30 2lc8-m6_A_A_29_A_30 2lc8-m7_A_A_29_A_30 2lc8-m8_A_A_29_A_30 2lc8-m9_A_A_29_A_30 2lc8-m10_A_A_30_C_31 2lc8-m1_A_A_30_C_31 2lc8-m2_A_A_30_C_31 2lc8-m3_A_A_30_C_31 2lc8-m4_A_A_30_C_31 2lc8-m5_A_A_30_C_31 2lc8-m6_A_A_30_C_31 2lc8-m7_A_A_30_C_31 2lc8-m8_A_A_30_C_31 2lc8-m9_A_A_30_C_31 2lc8-m10_A_C_31_C_32 2lc8-m1_A_C_31_C_32 2lc8-m2_A_C_31_C_32 2lc8-m3_A_C_31_C_32 2lc8-m4_A_C_31_C_32 2lc8-m5_A_C_31_C_32 2lc8-m6_A_C_31_C_32 2lc8-m7_A_C_31_C_32 2lc8-m8_A_C_31_C_32 2lc8-m9_A_C_31_C_32 2lc8-m10_A_C_32_C_33 2lc8-m1_A_C_32_C_33 2lc8-m2_A_C_32_C_33 2lc8-m3_A_C_32_C_33 2lc8-m4_A_C_32_C_33 2lc8-m5_A_C_32_C_33 2lc8-m6_A_C_32_C_33 2lc8-m7_A_C_32_C_33 2lc8-m8_A_C_32_C_33 2lc8-m9_A_C_32_C_33 2lc8-m10_A_C_33_A_34 2lc8-m1_A_C_33_A_34 2lc8-m2_A_C_33_A_34 2lc8-m3_A_C_33_A_34 2lc8-m4_A_C_33_A_34 2lc8-m5_A_C_33_A_34 2lc8-m6_A_C_33_A_34 2lc8-m7_A_C_33_A_34 2lc8-m8_A_C_33_A_34 2lc8-m9_A_C_33_A_34 2lc8-m10_A_A_34_G_35 2lc8-m1_A_A_34_G_35 2lc8-m2_A_A_34_G_35 2lc8-m3_A_A_34_G_35 2lc8-m4_A_A_34_G_35 2lc8-m5_A_A_34_G_35 2lc8-m6_A_A_34_G_35 2lc8-m7_A_A_34_G_35 2lc8-m8_A_A_34_G_35 2lc8-m9_A_A_34_G_35 2lc8-m10_A_G_35_G_36 2lc8-m1_A_G_35_G_36 2lc8-m2_A_G_35_G_36 2lc8-m3_A_G_35_G_36 2lc8-m4_A_G_35_G_36 2lc8-m5_A_G_35_G_36 2lc8-m6_A_G_35_G_36 2lc8-m7_A_G_35_G_36 2lc8-m8_A_G_35_G_36 2lc8-m9_A_G_35_G_36 2lc8-m10_A_G_36_A_37 2lc8-m1_A_G_36_A_37 2lc8-m2_A_G_36_A_37 2lc8-m3_A_G_36_A_37 2lc8-m4_A_G_36_A_37 2lc8-m5_A_G_36_A_37 2lc8-m6_A_G_36_A_37 2lc8-m7_A_G_36_A_37 2lc8-m8_A_G_36_A_37 2lc8-m9_A_G_36_A_37 2lc8-m10_A_A_37_U_38 2lc8-m1_A_A_37_U_38 2lc8-m2_A_A_37_U_38 2lc8-m3_A_A_37_U_38 2lc8-m4_A_A_37_U_38 2lc8-m5_A_A_37_U_38 2lc8-m6_A_A_37_U_38 2lc8-m7_A_A_37_U_38 2lc8-m8_A_A_37_U_38 2lc8-m9_A_A_37_U_38 2lc8-m10_A_U_38_A_39 2lc8-m1_A_U_38_A_39 2lc8-m2_A_U_38_A_39 2lc8-m3_A_U_38_A_39 2lc8-m4_A_U_38_A_39 2lc8-m5_A_U_38_A_39 2lc8-m6_A_U_38_A_39 2lc8-m7_A_U_38_A_39 2lc8-m8_A_U_38_A_39 2lc8-m9_A_U_38_A_39 2lc8-m10_A_A_39_A_40 2lc8-m1_A_A_39_A_40 2lc8-m2_A_A_39_A_40 2lc8-m3_A_A_39_A_40 2lc8-m4_A_A_39_A_40 2lc8-m5_A_A_39_A_40 2lc8-m6_A_A_39_A_40 2lc8-m7_A_A_39_A_40 2lc8-m8_A_A_39_A_40 2lc8-m9_A_A_39_A_40 2lc8-m10_A_A_40_C_41 2lc8-m1_A_A_40_C_41 2lc8-m2_A_A_40_C_41 2lc8-m3_A_A_40_C_41 2lc8-m4_A_A_40_C_41 2lc8-m5_A_A_40_C_41 2lc8-m6_A_A_40_C_41 2lc8-m7_A_A_40_C_41 2lc8-m8_A_A_40_C_41 2lc8-m9_A_A_40_C_41 2lc8-m10_A_C_41_C_42 2lc8-m1_A_C_41_C_42 2lc8-m2_A_C_41_C_42 2lc8-m3_A_C_41_C_42 2lc8-m4_A_C_41_C_42 2lc8-m5_A_C_41_C_42 2lc8-m6_A_C_41_C_42 2lc8-m7_A_C_41_C_42 2lc8-m8_A_C_41_C_42 2lc8-m9_A_C_41_C_42 2lc8-m10_A_C_42_C_43 2lc8-m1_A_C_42_C_43 2lc8-m2_A_C_42_C_43 2lc8-m3_A_C_42_C_43 2lc8-m4_A_C_42_C_43 2lc8-m5_A_C_42_C_43 2lc8-m6_A_C_42_C_43 2lc8-m7_A_C_42_C_43 2lc8-m8_A_C_42_C_43 2lc8-m9_A_C_42_C_43 2lc8-m10_A_C_43_U_44 2lc8-m1_A_C_43_U_44 2lc8-m2_A_C_43_U_44 2lc8-m3_A_C_43_U_44 2lc8-m4_A_C_43_U_44 2lc8-m5_A_C_43_U_44 2lc8-m6_A_C_43_U_44 2lc8-m7_A_C_43_U_44 2lc8-m8_A_C_43_U_44 2lc8-m9_A_C_43_U_44 2lc8-m10_A_U_44_C_45 2lc8-m1_A_U_44_C_45 2lc8-m2_A_U_44_C_45 2lc8-m3_A_U_44_C_45 2lc8-m4_A_U_44_C_45 2lc8-m5_A_U_44_C_45 2lc8-m6_A_U_44_C_45 2lc8-m7_A_U_44_C_45 2lc8-m8_A_U_44_C_45 2lc8-m9_A_U_44_C_45 2lc8-m10_A_C_45_A_46 2lc8-m1_A_C_45_A_46 2lc8-m2_A_C_45_A_46 2lc8-m3_A_C_45_A_46 2lc8-m4_A_C_45_A_46 2lc8-m5_A_C_45_A_46 2lc8-m6_A_C_45_A_46 2lc8-m7_A_C_45_A_46 2lc8-m8_A_C_45_A_46 2lc8-m9_A_C_45_A_46 2lc8-m10_A_A_46_A_47 2lc8-m1_A_A_46_A_47 2lc8-m2_A_A_46_A_47 2lc8-m3_A_A_46_A_47 2lc8-m4_A_A_46_A_47 2lc8-m5_A_A_46_A_47 2lc8-m6_A_A_46_A_47 2lc8-m7_A_A_46_A_47 2lc8-m8_A_A_46_A_47 2lc8-m9_A_A_46_A_47 2lc8-m10_A_A_47_A_48 2lc8-m1_A_A_47_A_48 2lc8-m2_A_A_47_A_48 2lc8-m3_A_A_47_A_48 2lc8-m4_A_A_47_A_48 2lc8-m5_A_A_47_A_48 2lc8-m6_A_A_47_A_48 2lc8-m7_A_A_47_A_48 2lc8-m8_A_A_47_A_48 2lc8-m9_A_A_47_A_48 2lc8-m10_A_A_48_G_49 2lc8-m1_A_A_48_G_49 2lc8-m2_A_A_48_G_49 2lc8-m3_A_A_48_G_49 2lc8-m4_A_A_48_G_49 2lc8-m5_A_A_48_G_49 2lc8-m6_A_A_48_G_49 2lc8-m7_A_A_48_G_49 2lc8-m8_A_A_48_G_49 2lc8-m9_A_A_48_G_49 2lc8-m10_A_G_49_U_50 2lc8-m1_A_G_49_U_50 2lc8-m2_A_G_49_U_50 2lc8-m3_A_G_49_U_50 2lc8-m4_A_G_49_U_50 2lc8-m5_A_G_49_U_50 2lc8-m6_A_G_49_U_50 2lc8-m7_A_G_49_U_50 2lc8-m8_A_G_49_U_50 2lc8-m9_A_G_49_U_50 2lc8-m10_A_U_50_C_51 2lc8-m1_A_U_50_C_51 2lc8-m2_A_U_50_C_51 2lc8-m3_A_U_50_C_51 2lc8-m4_A_U_50_C_51 2lc8-m5_A_U_50_C_51 2lc8-m6_A_U_50_C_51 2lc8-m7_A_U_50_C_51 2lc8-m8_A_U_50_C_51 2lc8-m9_A_U_50_C_51 2lc8-m10_A_C_51_G_52 2lc8-m1_A_C_51_G_52 2lc8-m2_A_C_51_G_52 2lc8-m3_A_C_51_G_52 2lc8-m4_A_C_51_G_52 2lc8-m5_A_C_51_G_52 2lc8-m6_A_C_51_G_52 2lc8-m7_A_C_51_G_52 2lc8-m8_A_C_51_G_52 2lc8-m9_A_C_51_G_52 2lc8-m10_A_G_52_G_53 2lc8-m1_A_G_52_G_53 2lc8-m2_A_G_52_G_53 2lc8-m3_A_G_52_G_53 2lc8-m4_A_G_52_G_53 2lc8-m5_A_G_52_G_53 2lc8-m6_A_G_52_G_53 2lc8-m7_A_G_52_G_53 2lc8-m8_A_G_52_G_53 2lc8-m9_A_G_52_G_53 2lc8-m10_A_G_53_G_54 2lc8-m1_A_G_53_G_54 2lc8-m2_A_G_53_G_54 2lc8-m3_A_G_53_G_54 2lc8-m4_A_G_53_G_54 2lc8-m5_A_G_53_G_54 2lc8-m6_A_G_53_G_54 2lc8-m7_A_G_53_G_54 2lc8-m8_A_G_53_G_54 2lc8-m9_A_G_53_G_54 2lc8-m10_A_G_54_G_55 2lc8-m1_A_G_54_G_55 2lc8-m2_A_G_54_G_55 2lc8-m3_A_G_54_G_55 2lc8-m4_A_G_54_G_55 2lc8-m5_A_G_54_G_55 2lc8-m6_A_G_54_G_55 2lc8-m7_A_G_54_G_55 2lc8-m8_A_G_54_G_55 2lc8-m9_A_G_54_G_55 2lc8-m10_A_G_55_G_56 2lc8-m1_A_G_55_G_56 2lc8-m2_A_G_55_G_56 2lc8-m3_A_G_55_G_56 2lc8-m4_A_G_55_G_56 2lc8-m5_A_G_55_G_56 2lc8-m6_A_G_55_G_56 2lc8-m7_A_G_55_G_56 2lc8-m8_A_G_55_G_56 2lc8-m9_A_G_55_G_56 2lc8-m10_A_G_56_G_57 2lc8-m1_A_G_56_G_57 2lc8-m2_A_G_56_G_57 2lc8-m3_A_G_56_G_57 2lc8-m4_A_G_56_G_57 2lc8-m5_A_G_56_G_57 2lc8-m6_A_G_56_G_57 2lc8-m7_A_G_56_G_57 2lc8-m8_A_G_56_G_57 2lc8-m9_A_G_56_G_57 2lc8-m10_A_G_57_C_58 2lc8-m1_A_G_57_C_58 2lc8-m2_A_G_57_C_58 2lc8-m3_A_G_57_C_58 2lc8-m4_A_G_57_C_58 2lc8-m5_A_G_57_C_58 2lc8-m6_A_G_57_C_58 2lc8-m7_A_G_57_C_58 2lc8-m8_A_G_57_C_58 2lc8-m9_A_G_57_C_58 2lc8-m10_A_C_58_A_59 2lc8-m1_A_C_58_A_59 2lc8-m2_A_C_58_A_59 2lc8-m3_A_C_58_A_59 2lc8-m4_A_C_58_A_59 2lc8-m5_A_C_58_A_59 2lc8-m6_A_C_58_A_59 2lc8-m7_A_C_58_A_59 2lc8-m8_A_C_58_A_59 2lc8-m9_A_C_58_A_59 step to class averages
____
____
____
Download Results as
csv or
json file.
Best NtC fitted to input structure. Restraints Restraints file for
REFMAC (steps with RMSD <= 0.5Å)
Commands file for
MMB (steps with RMSD <= 0.5Å)
Restraints file for
Phenix (steps with RMSD <= 0.5Å) [
? ]
User-based restraints REFMAC restraints for of NtCs and refinement output MMB commands for of NtCs and refinement output Phenix restraints for of NtCs [? ] and refinement output Definitions Average
parameters (csv) ,
esd values (csv) , and
Cartesian coordinates of conformers.
Download the papers Description of DNATCO server:
Černý et al., Nucleic Acids Research, 44, W284 (2016). Definition of conformers:
Schneider et al., Acta Cryst D, 74, 52-64 (2018). Example of application:
Schneider et al., Genes, 8(10), 278, (2017).