Conformers:
ABBIImiBZICOPNSYNN
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Human topoisomerase II alpha bound to DNA
Click a row in table or a step in viewer for analysis of results. Click column headers to sort data.
Steps with non-standard or missing atoms have not been assigned, description of conformers is defined in the table.
Results of the assignment of 28 detected steps in 1 model(s), can be also downloaded as csv or json file. Average confal 0, percentile 0.
Click a row in table or a step in viewer for analysis of results. Click column headers to sort data.
Define restraints for steps within Å cartesian RMSD, global sigma scaling factor or use per step sigma scaling.
| step number | Step name | CANA | NtC | confal | rmsd |
|---|---|---|---|---|---|
| 01 | 4fm9_C_DG1_DA2 | BBB | BB00 | 75 | 0.27 |
| 02 | 4fm9_C_DA2_DG3 | miB | BB10 | 92 | 0.14 |
| 03 | 4fm9_C_DG3_DG4 | B12 | BB04 | 58 | 0.15 |
| 04 | 4fm9_C_DG4_DA5 | B12 | BB04 | 77 | 0.18 |
| 05 | 4fm9_C_DA5_DT6 | BBw | BB02 | 18 | 0.26 |
| 06 | 4fm9_C_DT6_DG7 | miB | BB15 | 49 | 0.31 |
| 07 | 4fm9_C_DG7_DA8 | B12 | BB04 | 76 | 0.19 |
| 08 | 4fm9_C_DA8_DC9 | NAN | NANT | 0 | 0.55 |
| 09 | 4fm9_C_DC9_DG10 | NAN | NANT | 0 | 0.60 |
| 10 | 4fm9_C_DG10_DA11 | B12 | BB04 | 92 | 0.14 |
| 11 | 4fm9_C_DA11_DT12 | B-A | BA10 | 95 | 0.12 |
| 12 | 4fm9_C_DT12_DG13 | NAN | NANT | 0 | 0.41 |
| 13 | 4fm9_D_DC1_DG2 | AAA | AA00 | 71 | 0.20 |
| 14 | 4fm9_D_DG2_DC3 | AAA | AA00 | 80 | 0.24 |
| 15 | 4fm9_D_DC3_DG4 | AAA | AA08 | 74 | 0.24 |
| 16 | 4fm9_D_DG4_DC5 | AAA | AA00 | 63 | 0.29 |
| 17 | 4fm9_D_DC5_DA6 | AAA | AA00 | 61 | 0.23 |
| 18 | 4fm9_D_DA6_DT7 | A-B | AB05 | 70 | 0.35 |
| 19 | 4fm9_D_DT7_DC8 | NAN | NANT | 0 | 0.62 |
| 20 | 4fm9_D_DC8_DG9 | NAN | NANT | 0 | 0.56 |
| 21 | 4fm9_D_DG9_DT10 | BBw | BB02 | 51 | 0.32 |
| 22 | 4fm9_D_DT10_DC11 | miB | BB15 | 52 | 0.47 |
| 23 | 4fm9_D_DC11_DA12 | B12 | BB04 | 34 | 0.16 |
| 24 | 4fm9_D_DA12_DT13 | BBw | BB02 | 32 | 0.42 |
| 25 | 4fm9_D_DT13_DC14 | BBB | BB00 | 53 | 0.25 |
| 26 | 4fm9_D_DC14_DC15 | BBB | BB00 | 89 | 0.19 |
| 27 | 4fm9_D_DC15_DT16 | BBB | BB00 | 93 | 0.25 |
| 28 | 4fm9_D_DT16_DC17 | B-A | BA01 | 31 | 0.23 |
Steps with non-standard or missing atoms have not been assigned, description of conformers is defined in the table.
|
step: Table of conformers |
| δ1 | ε1 | ζ1 | α2 | β2 | γ2 | δ2 | χ1 | χ2 | μ | NN | CC | |
| step_torsions | ||||||||||||
| ntC_average | ||||||||||||
| Δ torsions | ||||||||||||
| torsion scores |
| comments | step confal = NaN cartesian RMSD = NaN Å pseudorotation: NA details: NA |
Similarity of step to class averages
Download
Results as csv or json file.Best NtC fitted to input structure.
Restraints
Restraints file for REFMAC (steps with RMSD <= 0.5Å)Commands file for MMB (steps with RMSD <= 0.5Å)
Restraints file for Phenix (steps with RMSD <= 0.5Å) [?]
Definitions
Average parameters (csv), esd values (csv), and Cartesian coordinates of conformers.Download the papers
Description of DNATCO server:Černý et al., Nucleic Acids Research, 44, W284 (2016).
Definition of conformers:
Schneider et al., Acta Cryst D, 74, 52-64 (2018).
Example of application:
Schneider et al., Genes, 8(10), 278, (2017).
Browse conformers
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