Conformers:
ABBIImiBZICOPNSYNN
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Human topoisomerase IIbeta in complex with DNA and etoposide
Click a row in table or a step in viewer for analysis of results. Click column headers to sort data.
Steps with non-standard or missing atoms have not been assigned, description of conformers is defined in the table.
Results of the assignment of 36 detected steps in 1 model(s), can be also downloaded as csv or json file. Average confal 0, percentile 0.
Click a row in table or a step in viewer for analysis of results. Click column headers to sort data.
Define restraints for steps within Å cartesian RMSD, global sigma scaling factor or use per step sigma scaling.
| step number | Step name | CANA | NtC | confal | rmsd |
|---|---|---|---|---|---|
| 01 | 3qx3_C_DA1_DG2 | NAN | NANT | 0 | 0.33 |
| 02 | 3qx3_C_DG2_DC3 | BB2 | BB07 | 57 | 0.36 |
| 03 | 3qx3_C_DC3_DC4 | B-A | BA05 | 10 | 0.38 |
| 04 | 3qx3_C_DC4_DG5 | NAN | NANT | 0 | 0.55 |
| 05 | 3qx3_C_DG5_DA6 | BB2 | BB07 | 75 | 0.28 |
| 06 | 3qx3_C_DA6_DG7 | B-A | BA10 | 95 | 0.00 |
| 07 | 3qx3_C_DG7_DC8 | AAA | AA00 | 65 | 0.27 |
| 08 | 3qx3_D_DT9_DG10 | A-B | AB03 | 62 | 0.23 |
| 09 | 3qx3_D_DG10_DC11 | B-A | BA01 | 25 | 0.25 |
| 10 | 3qx3_D_DC11_DA12 | AAA | AA02 | 82 | 0.16 |
| 11 | 3qx3_D_DA12_DG13 | NAN | NANT | 0 | 0.29 |
| 12 | 3qx3_D_DG13_DC14 | AAA | AA00 | 81 | 0.29 |
| 13 | 3qx3_D_DC14_DT15 | A-B | AB01 | 50 | 0.29 |
| 14 | 3qx3_D_DT15_DC16 | NAN | NANT | 0 | 0.65 |
| 15 | 3qx3_D_DC16_DG17 | NAN | NANT | 0 | 0.43 |
| 16 | 3qx3_D_DG17_DG18 | BBB | BB00 | 86 | 0.21 |
| 17 | 3qx3_D_DG18_DC19 | B-A | BA05 | 81 | 0.19 |
| 18 | 3qx3_D_DC19_DT20 | AAA | AA02 | 53 | 0.55 |
| 19 | 3qx3_E_DA1_DG2 | BBB | BB00 | 68 | 0.31 |
| 20 | 3qx3_E_DG2_DC3 | B12 | BB04 | 83 | 0.21 |
| 21 | 3qx3_E_DC3_DC4 | NAN | NANT | 0 | 0.54 |
| 22 | 3qx3_E_DC4_DG5 | A-B | AB01 | 15 | 0.58 |
| 23 | 3qx3_E_DG5_DA6 | BB2 | BB07 | 72 | 0.24 |
| 24 | 3qx3_E_DA6_DG7 | B-A | BA10 | 94 | 0.05 |
| 25 | 3qx3_E_DG7_DC8 | AAA | AA00 | 64 | 0.26 |
| 26 | 3qx3_F_DT9_DG10 | BBB | BB00 | 32 | 0.30 |
| 27 | 3qx3_F_DG10_DC11 | B-A | BA01 | 44 | 0.25 |
| 28 | 3qx3_F_DC11_DA12 | AAA | AA02 | 91 | 0.15 |
| 29 | 3qx3_F_DA12_DG13 | NAN | NANT | 0 | 0.71 |
| 30 | 3qx3_F_DG13_DC14 | AAA | AA00 | 80 | 0.28 |
| 31 | 3qx3_F_DC14_DT15 | A-B | AB01 | 39 | 0.33 |
| 32 | 3qx3_F_DT15_DC16 | NAN | NANT | 0 | 0.66 |
| 33 | 3qx3_F_DC16_DG17 | NAN | NANT | 0 | 0.64 |
| 34 | 3qx3_F_DG17_DG18 | BBB | BB00 | 93 | 0.18 |
| 35 | 3qx3_F_DG18_DC19 | B-A | BA05 | 17 | 0.28 |
| 36 | 3qx3_F_DC19_DT20 | A-B | AB03 | 61 | 0.42 |
Steps with non-standard or missing atoms have not been assigned, description of conformers is defined in the table.
|
step: Table of conformers |
| δ1 | ε1 | ζ1 | α2 | β2 | γ2 | δ2 | χ1 | χ2 | μ | NN | CC | |
| step_torsions | ||||||||||||
| ntC_average | ||||||||||||
| Δ torsions | ||||||||||||
| torsion scores |
| comments | step confal = NaN cartesian RMSD = NaN Å pseudorotation: NA details: NA |
Similarity of step to class averages
Download
Results as csv or json file.Best NtC fitted to input structure.
Restraints
Restraints file for REFMAC (steps with RMSD <= 0.5Å)Commands file for MMB (steps with RMSD <= 0.5Å)
Restraints file for Phenix (steps with RMSD <= 0.5Å) [?]
Definitions
Average parameters (csv), esd values (csv), and Cartesian coordinates of conformers.Download the papers
Description of DNATCO server:Černý et al., Nucleic Acids Research, 44, W284 (2016).
Definition of conformers:
Schneider et al., Acta Cryst D, 74, 52-64 (2018).
Example of application:
Schneider et al., Genes, 8(10), 278, (2017).
Browse conformers
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