Conformers:
ABBIImiBZICOPNSYNN
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Human Topoisomerase I Ara-C Complex
Click a row in table or a step in viewer for analysis of results. Click column headers to sort data.
Steps with non-standard or missing atoms have not been assigned, description of conformers is defined in the table.
Results of the assignment of 39 detected steps in 1 model(s), can be also downloaded as csv or json file. Average confal 0, percentile 0.
Click a row in table or a step in viewer for analysis of results. Click column headers to sort data.
Define restraints for steps within Å cartesian RMSD, global sigma scaling factor or use per step sigma scaling.
| step number | Step name | CANA | NtC | confal | rmsd |
|---|---|---|---|---|---|
| 01 | 1nh3_B_DA1_DA2 | BBB | BB00 | 86 | 0.17 |
| 02 | 1nh3_B_DA2_DA3 | BBB | BB00 | 81 | 0.29 |
| 03 | 1nh3_B_DA3_DA4 | BBB | BB00 | 69 | 0.30 |
| 04 | 1nh3_B_DA4_DA5 | BBB | BB00 | 51 | 0.21 |
| 05 | 1nh3_B_DA5_DG6 | BBB | BB00 | 58 | 0.39 |
| 06 | 1nh3_B_DG6_DA7 | BBB | BB00 | 69 | 0.21 |
| 07 | 1nh3_B_DA7_DC8 | B12 | BB04 | 51 | 0.37 |
| 08 | 1nh3_B_DC8_DU9 | B12 | BB04 | 51 | 0.36 |
| 09 | 1nh3_C_DG12_DA13 | BBB | BB00 | 78 | 0.24 |
| 10 | 1nh3_C_DA13_DA14 | BBB | BB00 | 67 | 0.25 |
| 11 | 1nh3_C_DA14_DA15 | B12 | BB04 | 59 | 0.23 |
| 12 | 1nh3_C_DA15_DA16 | BBB | BB00 | 66 | 0.29 |
| 13 | 1nh3_C_DA16_DA17 | B12 | BB04 | 80 | 0.26 |
| 14 | 1nh3_C_DA17_DU18 | NAN | NANT | 0 | 0.42 |
| 15 | 1nh3_C_DU18_DU19 | BBw | BB03 | 76 | 0.20 |
| 16 | 1nh3_C_DU19_DU20 | BBB | BB00 | 62 | 0.30 |
| 17 | 1nh3_C_DU20_DU21 | BBw | BB11 | 52 | 0.24 |
| 18 | 1nh3_C_DU21_DT22 | NAN | NANT | 0 | 0.63 |
| 19 | 1nh3_D_DA101_DA102 | NAN | NANT | 0 | 1.37 |
| 20 | 1nh3_D_DA102_DA103 | BBB | BB00 | 62 | 0.33 |
| 21 | 1nh3_D_DA103_DA104 | BBB | BB00 | 51 | 0.30 |
| 22 | 1nh3_D_DA104_DA105 | BBB | BB00 | 78 | 0.24 |
| 23 | 1nh3_D_DA105_DT106 | BBw | BB02 | 50 | 0.31 |
| 24 | 1nh3_D_DT106_DU107 | BBB | BB00 | 77 | 0.21 |
| 25 | 1nh3_D_DU107_DU108 | BBB | BB00 | 80 | 0.24 |
| 26 | 1nh3_D_DU108_DU109 | BBB | BB00 | 82 | 0.26 |
| 27 | 1nh3_D_DU109_DU110 | NAN | NANT | 0 | 0.49 |
| 28 | 1nh3_D_DU110_DC111 | BBw | BB02 | 20 | 0.48 |
| 29 | 1nh3_D_DC111_CAR112 | NAN | NANT | 0 | 0.38 |
| 30 | 1nh3_D_CAR112_DA113 | NAN | NANT | 0 | 0.38 |
| 31 | 1nh3_D_DA113_DA114 | BBB | BB00 | 36 | 0.33 |
| 32 | 1nh3_D_DA114_DG115 | BBw | BB02 | 16 | 0.39 |
| 33 | 1nh3_D_DG115_DU116 | BBB | BB00 | 49 | 0.37 |
| 34 | 1nh3_D_DU116_DC117 | BBB | BB00 | 84 | 0.14 |
| 35 | 1nh3_D_DC117_DU118 | BBw | BB03 | 33 | 0.56 |
| 36 | 1nh3_D_DU118_DU119 | NAN | NANT | 0 | 0.52 |
| 37 | 1nh3_D_DU119_DU120 | BBw | BB02 | 35 | 0.37 |
| 38 | 1nh3_D_DU120_DU121 | BBB | BB00 | 63 | 0.18 |
| 39 | 1nh3_D_DU121_DT122 | BBB | BB00 | 55 | 0.25 |
Steps with non-standard or missing atoms have not been assigned, description of conformers is defined in the table.
|
step: Table of conformers |
| δ1 | ε1 | ζ1 | α2 | β2 | γ2 | δ2 | χ1 | χ2 | μ | NN | CC | |
| step_torsions | ||||||||||||
| ntC_average | ||||||||||||
| Δ torsions | ||||||||||||
| torsion scores |
| comments | step confal = NaN cartesian RMSD = NaN Å pseudorotation: NA details: NA |
Similarity of step to class averages
Download
Results as csv or json file.Best NtC fitted to input structure.
Restraints
Restraints file for REFMAC (steps with RMSD <= 0.5Å)Commands file for MMB (steps with RMSD <= 0.5Å)
Restraints file for Phenix (steps with RMSD <= 0.5Å) [?]
Definitions
Average parameters (csv), esd values (csv), and Cartesian coordinates of conformers.Download the papers
Description of DNATCO server:Černý et al., Nucleic Acids Research, 44, W284 (2016).
Definition of conformers:
Schneider et al., Acta Cryst D, 74, 52-64 (2018).
Example of application:
Schneider et al., Genes, 8(10), 278, (2017).
Browse conformers
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| Color by conformation group (pyramids) | |
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